What’s The Best Oxaloacetate Supplement?

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Recommended oxaloacetic acid supplement
What Are the Best Oxaloacetate Supplements?
Reviewed by the BioHackers Lab Team | Last updated: August 31, 2020

I was interested to find out what are some of the best oxaloacetate supplements for me to review.

Utilizing a high quality supplement that contains oxaloacetate might help protect brain health, help regulate glucose control & be use to help increase a longer life span.

So I went out researching online, and using some myself, for what are some of the highest rated & most recommended oxaloacetate products and brands available to buy online.

Top Rated Oxaloacetate Supplements in 2024

The list of recommended oxaloacetate supplements for you to compare.

1. benaGene – Original Supplier


Brand Name Active Ingredient Dosage Type Supplied Amount
benaGene 100mg Capsules 30 Capsules

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The beneGene oxaloacetate supplement on Amazon is manufactured by Terra Biological LLC and is just one of the supplements created by this brand that aims to provide neurological protection based off of a glucose-supporting supplementation.

All benaGene products are created on site and undergo a rigorous quality control process in order to ensure their safety as well as their effectiveness.

I trust the products that come from Terra Biological LLC because customer service is always a priority and always-increasing standards sets this brand apart from other nutritional supplement creators and companies.

The benaGene 30 capsule product provides 100mg of oxaloacetate as well as 150mg of vitamin C.

This dosage is scientifically designed to mimic the caloric content of a fasting diet without having to reduce calorie intake. The process of fasting has proven to be beneficial when it comes to neurological health and overall well-being. (ref)

What beneGene allows the body to do is have a more efficient metabolic process while allowing cells in the body to function optimally.

Providing the body with more oxaloacetate than it has already occurring in the body also results in more energy throughout the day. This study looked at testing this supplement to help increase the life span of worms when taken long-term.

Oxaloacetate is used in bodily functions like synthesis of amino acids, the process of metabolizing and utilizing citric acid, fatty acid synthesis and the cycle of urea in the body.

The product is designed to work as the oxaloacetate supplement builds up in the body over time. There typically is not an immediate burst of energy or noticeable effects, but long term use promotes better oxaloacetate efficiency in the body which in turn promotes a longer and healthier life in essence.

The product should be taken at the same time each day with food.

  • Optimal dose is 100 mg (with 150 mg of Vitamin C)
  • Easy to swallow, coated capsules
  • This minimal dose of oxaloacetate is enough to promote better neurological and metabolic function but negative side effects are not reported in this dosage.
  • The product is non-habit forming and can be stopped at any time with no reported side effects.
  • No artificial colors or unwanted fillers are used in the production of this product.
  • Some users mention it can be difficult to know if it is making a difference as they can’t feel anything.

2. AOR beneGene

Amazon Echo Dot

  • Low dose providing enough supplementation for results but nothing excessive that will cause side effects.
  • Each dose contains Vitamin B6 (100 mg), Calcium, as calcium carbonate, (230 mg), Sodium (25 mg), Carnosine (1000 mg), ArginoCarn® Acetyl-L-carnitine arginate dihydrochloride (675 mg), R-Lipoic Acid (150mg), BioPQQ® Pyrroloquinoline quinone disodium salt (10 mg).
  • 120 capsule supply in each bottle
  • Four capsules are to be consumed at one time
  • Thirty day supply

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The goal of AOR is to provide products that are based on quality, purity and potency.

Advanced Orthomolecular Research Only the highest quality of raw materials are used by Life Extension without the use of chemicals, artificial ingredients or unnecessary fillers.

Each capsule contains 100 mg of oxaloacetate along with 100 mg of vitamin C.

  • Contains specially formulated ingredients that are available only through Life Extension.
  • A convenient product that is designed to help people achieve weigh loss goals, increase their overall energy, increase alertness and promote an overall high level of health and well-being.
  • Contains no alcohol, high fructose corn syrup, artificial ingredients, artificial colors or additives.
  • A non-habit forming product, you can discontinue its use at any time if you are not happy with the results that you are seeing.
  • Some users mention it can be difficult to know if it is making a difference as they can’t feel anything.

3. Bulletproof KetoPrime

Brand Name Active Ingredient Dosage Type Supplied Amount
KetoPrime 100mg Lozenges 30 Lozenges

How to Take KetoPrime
  • KetoPrime can be taken at any time of day, with or without food.
  • Thirty lozenges provide a one month supply of this product.
  • Product is to be slowly melted for approximately ten minutes. At this time you can chew and swallow the product.
  • If you are feeling tired or bogged down, you can use this product at that time.
  • This product is frequently used by athletes prior to physical activity in order to achieve a boost in energy during performance.
  • Provides energy, but also the ability to better focus that energy on a positive outcome and goal.

Providing energy at a cellular level, this product provides impressive results in a short amount of time.

Constructed with other beneficial ingredients that help with absorption, so your body receives as much as 90 percent of the supplements you are consuming.

A convenient lozenge that is easy to consume, and easy to take on the go if needed.

Reduces glutamate buildup in the body which can lead to excessive brain fog if left untreated.

You get clean energy without the use of products that can leave you feeling jittery, anxious or leave you with an energy crash.

Customer reviews and product explanations leave you with the impression that this product was created meticulously with the most high quality ingredients available and with the best science in mind.

  • Non habit forming
  • Product also contains vitamin C to allow for better absorption
  • Following a ketogenic diet can help increase the potential of this product as well as other oxaloacetate products.
  • This product works best when taken at a point in the day where energy level is low and metabolism feeling sluggish. This can vary from one person to another and should be considered when purchasing the product.
  • Some users mention it can be difficult to know if it is making a difference as they can’t feel anything.

Frequently asked Questions

It is important to shop for the best option when it comes to an oxaloacetate product, however, having some background information on the supplement can help you make an educated decision.

What is Oxaloacetate?

Oxaloacetate (OAA) is an organic compound that plays a role in a number of neurophysiological processes in the body. It assists in the synthesis of amino acids, synthesis of citric acid, synthesis of fatty acids and plays a role in the urea cycle of the body.

How Does Oxaloacetate Work?

Oxaloacetate is considered to be a main contributor in the Kreb’s cycle in the body, and is thought to protect the brain’s neurons and decreases inflammation in the brain.

This can result in more efficient bodily functions, better brain function, more energy, increase metabolism and a lower risk of stroke. (ref)

Benefits of Oxaloacetate

All of these benefits can indicate an increased focus on improving brain health and overall health.

When to Use Oxaloacetate

Oxaloacetic acid suggested usage:

They would use it in order to increase productivity, increase energy and provide better and more optimal health overall. This in turn, can increase a person’s life span.

Recommended Dosage

Most oxaloacetate supplements contain 100 mg of oxaloacetate per recommended daily dose, along with 100 mg of ascorbic acid.

There is unpublished research results for Alzheimer patients on taking doses of 1-2 grams per day for up to 4 weeks. (ref)

Possible Side-Effects


Based on current research reviewed, there does not currently seem to be any dangerous side effects associated with oxaloacetate supplementation.

However, there hasn’t been a great deal of studies done on humans especially at different dosage levels so caution is advised.

More research will need to be done in the future to rule out any long-term issues with ongoing consumption of oxaloacetate.

Foods That Contain Oxaloacetate

Oxaloacetate is said to be found naturally in most foods. Foods that contain malic acid might be useful as our body converts malic acid to oxaloacetate. (ref)

How to Test Oxaloacetate Levels

There is no lab test or scan currently available to test a persons’ oxaloacetate levels.

There are no documented optimal, low or high level ranges for oxaloacetate testing in humans.

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