What Are The Best Resveratrol Supplements?

The best resveratrol supplement brands are:

Why do people take resveratrol supplements? It is because resveratrol is thought to work synergistically with NMN supplements. This is why people look to supplement with resveratrol to help provide anti-oxidant & potential longevity effects.

… recent studies have revealed Resveratrol as a known activator of the protein deacetylase sirtuin 1 (SIRT1) gene …

The Sirtuin System: The Holy Grail of Resveratrol?

I was interested to find out what are some of the best resveratrol supplements on the market for me to review.

So, I went out researching online for what are some of the highest rated & most recommended resveratrol supplement products and brands available to buy online.

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What Is the Best Resveratrol Brand on the Market?

If you’re looking for the best resveratrol brand, we would recommend ProHealth Longevity. The brand has been in operation since 1988, provide a certificate of analysis to reassure about ingredient quality and use a top tier resveratrol ingredient source, this makes ProHealth Longevity the top resveratrol brand choice.

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The Best Resveratrol Supplements in 2025

Here is the list of recommended resveratrol supplements on the market we reviewed for you to compare.

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1. ProHealth Micronized Trans-Resveratrol Powder

ProHealth have been making dietary supplements since 1988 and specialize in supplements of interest in the field of longevity and healthspan. They produce a micronized trans-resveratrol powder that contains no other ingredients and you can view the third party certificate of analysis for the 98% plus purity claim. We could see they use Veri-te™ resveratrol as the ingredient source; guaranteed to be polycyclic aromatic hydrocarbon (PAH) and emodin free. You can also get their ProHealth Trans-Resveratrol in a capsule form, but take note this product also contains a proprietary blend of other polyphenols.

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2. Renue By Science Trans-Resveratrol Powder

Reneu by Science are a company that I have spoken with and they are passionate about providing the best quality products in the longevity supplement space that have certificates of analysis to prove their purity. I think they produce the best trans-resveratrol supplement as it is 100% trans-resveratrol with no added ingredients.

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3. Do Not Age Pure Resveratrol Capsules

Do Not Age is a brand that is one of the market leaders in healthspan supplements; can ship their trans-resveratrol worldwide. They display their Pure Resveratrol products’ certificate of analysis on the product page. You can buy their supplements in 60 capsule (30 days of servings) or 366 capsule (183 days of servings) tubs.

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4. Purely Beneficial Resveratrol

Based in Sacramento, California, Purely Beneficial “is dedicated to providing the purest health supplements” available. They sell a number of supplements, including apple cider vinegar, elderberry, tart cherry, charcoal and others. Their resveratrol is a blend of 605 milligrams plus other antioxidants. (ref)

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5. MAAC10 Trans-Resveratrol Capsules

MAAC10 is company with its headquarters located in Lake Worth, Florida. Their website says they committed to the idea that mitochondrial health and cellular respiration are the keys to wellness. They pride themselves on a holistic approach and they have tons of informative content on their website, specifically on the science behind their products. They sell nicotinamide mononucleotide, NADH + CoQ10. Their resveratrol formula includes Bioperene, which is said to help the resveratrol to bypass the liver and go directly into the bloodstream. (ref)

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6. Toniiq Trans-Resveratrol Supplement

Toniiq is a brand that is getting lots of good reviews online from what we can see. We found there is a certificate of authenticity on one of the Amazon customer reviews, however, the company doesn’t display any CoA certificate on their website for any products. (ref)

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7. Purest Vantage Resveratrol Supplement

Purest Vantage is dedicated to creating high quality supplements that help people maintain optimal health. They are also committed to quality and take pride in their contaminant-free products. They offer several supplements including magnesium oil, activated charcoal and B-complex in addition to resveratrol. Their website doesn’t have much else to offer, but you can contact them at their headquarters in Orlando, Florida. Their resveratrol is a blend, containing 600 milligrams of resveratrol plus antioxidants. (ref)

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8. Life Extension Optimized Resveratrol

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Life Extension has a huge inventory of herbs, supplements and skincare products. They have been around for over 35 years and make over 350 different supplements. One of the most useful features of their website is their “Supplement Finder,” where users can input some basic information and find out which supplements are right for them. Life Extension also offers lab testing services and an educational magazine. (ref)

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9. Bulk Supplements Resveratrol Powder

BulkSupplements is a company based in Henderson, Nevada and being true to their name offer over 400 different supplements and ingredients. They are the only brand we found that sell resveratrol in small amounts and bulk amounts. So, you can buy a small the amount with only 10 servings all the way up to 1 kg bags with 1000 servings. They also sell resveratrol capsules for those who don’t want the powdered form. (ref)

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10. Jarrow Formulas Resveratrol

Jarrow Formulas has been making and supplying supplements since 1977. Their scientific panel ensures the quality and integrity of each product. Their website features a database of all their products, as well as a store locator so customers can easily find them. The company has received numerous awards for product quality since 2002. Their resveratrol supplement contains the full dose in one capsule, so it is that much easier to take. (ref)

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How to Choose a Resveratrol Supplement

These are the things to consider before buying a resveratrol supplement:

1. Is the resveratrol used 100% trans-resveratrol
2. Is the source of resveratrol from Japanese Knotweed plant (a.k.a Polygonum) or via fermentation
3. Does the brand provide a certificate of analysis to prove purity and validation that it contains the amount of active ingredient as advertised per serving dose
4. What is the dose per serving to make sure you get the amount of resveratrol that you want
5. What type of form does the resveratrol come in e.g. powder, tablet, capsule, sublingual liquid etc…
6. Are there any other active ingredients in the product that you want or not
7. What is the cost per serving to see which product is the best deal or most cost effective for you
8. What is the shipping policy of the brand to make sure you can get it delivered to you
9. Do people mention the brand as a recommended choice on popular online forums

We have seen people who take resveratrol also are looking at these other mitochondria health supplements:

• Nicotinamide riboside
• Nicotinamide mononucleotide
• NAD+
• Spermidine
• Oxaloacetate
• CoQ10

What is Resveratrol?

Resveratrol is a chemical found naturally in certain foods such as grapes, mulberries, red wine and peanuts. In plants, it is produced to defend against fungal infections and other threats. (ref)

In humans, it is often used as a medicine for high cholesterol, heart disease and even cancer, although there is still not a lot of evidence around its effectiveness. (ref)

What Are the Types of Resveratrol?

The two forms of resveratrol are cis-resveratrol and trans-resveratrol. Trans-resveratrol is the most biological active form of resveratrol, which is why you will see it most resveratrol supplement nutrition labels.

What Are the Benefits of Resveratrol?

Resveratrol has been studied at different levels of evidence to see what are the potential beneficial effects it may have. Studies range from effects on yeast, mice and some human studies. (ref)

Here are some of the potential benefits of resveratrol that have been mentioned in research studies:

• May help with hay fever when using a nasal spray of resveratrol
• May help aid weight loss in overweight and obese adults on a weight loss program
• May improve mood
• May help with blood sugar control and insulin resistance in diabetes
• May treat polycystic ovary syndrome
• May reduce inflammation
• May inhibit cancer cells
• May protect against glaucoma and neurodegeneration
• May inhibit growth of and destroy biofilms
• Might have the potential to increase longevity
• May reduce acne
• May reduce hay fever symptoms
• May improve mental function in menopausal women
• May help decrease body fat in those with metabolic syndrome
• May reduce pain and swelling in those with rheumatoid arthritis
• May slow skin aging
• May reduce symptoms of ulcerative colitis
• May speed up peritoneal dialysis
• May help with lung disease
• May reduce blood pressure
• May improve heart function in patients with cardiovascular disease

(Source)

When to Take Resveratrol?

A 2012 study showed that a 2,000 milligram dose of trans-resveratrol twice a day was tolerated well when taken with a meal that was not high in fat. Diarrhea was the only major side effect observed. (ref)

What is the Best Resveratrol Dosage to Take?

We could find no clear consensus on what is the optimal resveratrol dosage to take for bioavailability.

According to MedlinePlus a dose of 250-1000 mg of resveratrol supplementation by mouth daily for up to 3 months is used by most adults.

David Sinclair has said publicly in the past that he takes 500 mg – 1 gram of resveratrol in the morning with yoghurt.

The health benefits of resveratrol are very much dependent on dose. It can be beneficial for a variety of conditions when taken in low doses, but high doses can actually worsen some illnesses. (ref)

For specifics, we can look at animal studies, which have demonstrated positive effects of various dosages. While these numbers are supported by evidence, they are not infallible.

Is It Safe to Take Resveratrol?

According to various clinical trials taking trans-resveratrol supplementation was safe and well tolerated at different doses. Resveratrol doses between 2.5 g and 5 g per day are more likely to cause physical side-effects.

We did also find valid concerns that taking polyphenol supplements, like resveratrol, could be dangerous for certain subpopulations, especially at higher doses like 2 g per day.

Possible Side-Effects

When taken as a food, there are rarely any side effects. But, there are also some potential serious risks when taking resveratrol in supplement form. (ref)

Side effects can include:

• Mild to moderate stomach upset and diarrhea
• Slowed blood clotting
• Increased estrogen exposure

Resveratrol should be avoided if you are pregnant or breastfeeding, have a bleeding disorder, have a hormone-sensitive cancer or are having surgery. (ref)

Frequently Asked Questions

Sources

• Science Direct, Resveratrol
• Salehi et al. 2018. Resveratrol: A Double-Edged Sword in Health Benefits
• Ramírez-Garza et al. 2018. Health Effects of Resveratrol: Results from Human Intervention Trials
• Resveratrol: MedlinePlus Supplements
• Duda-Chodak et al. 2023. Possible Side Effects of Polyphenols and Their Interactions with Medicines
• WebMD, Resveratrol – Uses, Side Effects, And More
• Farzaei et al. 2017. Effect of resveratrol on cognitive and memory performance and mood: A meta-analysis of 225 patients
• Berman et al. 2017. The therapeutic potential of resveratrol: a review of clinical trials
• Porte et al. 2010. Steady-State Pharmacokinetics and Tolerability of Trans-Resveratrol 2000mg Twice Daily with Food, Quercetin and Alcohol (Ethanol) in Healthy Human Subjects
• Mukherjee et al. 2010. Dose-Dependency of Resveratrol in Providing Health Benefits