What Are the Best NAD+ Supplements?

The Best NAD Booster Supplement Brands for 2023

The best nicotinamide adenine dinucleotide (NAD) supplement brands are:

Taking a good NAD+ supplement is thought to help boost your NAD levels, which could support energy production in our mitochondria, help repair DNA and support other systems in the body.

I was interested to find out what are some of the best nicotinamide adenine dinucleotide (NAD) supplements for me to review.

So, I went out researching online for what are some of the highest rated & most recommended NAD+ supplement products and brands available to buy online.

What Is the Best NAD Brand on the Market?

Renue By Science is our favourite NAD supplement brand on the market. This is because they have been in the market for several years now, they offer the widest range of NAD boosting ingredients like NAD, NMN and NR, you can get these active ingredients in different forms from liposomal capsules to bulk powders and convenient lozenges, they are a leader in transparency in their ingredient sourcing and providing certificates of analysis to assure customers they are getting what they are promised on the label.

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The Best NAD+ Supplements in 2024

Here is a list of recommended NAD+ supplements on the market we reviewed for you to compare.

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1. Renue By Science Lipo NAD+ Complete

Renue By Science (previously known as Alive By Nature and Alive By Science) makes a unique 3-in-1 NAD supplement product, which contains NAD, NMN and NR wrapped in liposomes that are said to protect the active ingredients and help get them into the bloodstream. The say they created the first ever sublingual NMN supplement. They market themselves as triple lab tested for quality assurance and do provide the COA certificates on their product pages we reviewed.

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2. ProHealth Longevity NMN Pro 150 Tablets

The ProHealth Longevity NMN supplement is an interesting option as they state they have the highest quality NMN available. This is because they source the NMN they sell from the biotech company that supplied the product for the first human research trial on NMN safety. They also state they have a NMN product that is stable at room temperature. The one thing to note is that the tablets also contain organic rice flour. (ref)

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3. Do Not Age NMN Capsules

Do Not Age is a NMN brand that sells a lot of longevity specific supplements including pure NMN. They sell NMN capsules only, so no powder option. Their suggested serving is to take 2 capsules to get a 1000mg dose. Do Not Age guarantee the purity of the product on delivery to you as they say that they refrigerate the NMN right until the courier collects it from them. They do provide their latest certificate of analysis proof on their product page when we reviewed it.

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4. Tru Niagen Nicotinamide Riboside

Tru Niagen uses NIAGEN, the patented NR product owned by ChromaDex,. Dr. Charles Brenner PhD. who discovered nicotinamide riboside can help raise NAD levels in 2004, is on the scientific advisory board. The Tru Niagen website offers a lot of educational insight on the science behind why nicotinamide riboside is important for cellular function. (ref)

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5. Wonderfeel Youngr NMN Capsules

The Wonderfeel brand are a US brand from San Francisco who have been in operation since 2018. The Wonderfeel Youngr NMN supplement was developed by Andrew Salzman, MD. You are able to ask for their recent certificate of analysis by emailing support; it is not published on the website. The 900 mg dosage of NMN is said to be based on research papers finding that amount appears to be the best.

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6. Thorne NiaCel 400 Nicotinamide Riboside

The Thorne NiaCel 400 formulation is a good option for someone wanting a NR supplement that combines both NR and betaine anhydrous to possibly help enhance their NAD levels. This product contains 85 mg of betaine anhydrous. (ref)

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7. Elysium Health Basis NR Supplement

Elysium Health Basis supplement is contains a patent pending form of NR called crystalline nicotinamide riboside (NR-E). The product also contains 50mg of Pterostilbene which is said to work together with the NR to help boost NAD+ levels. The product is NSF Certified for Sport and they link to their ingredient quality lots testing results. Their products was also shown in an RCT study to increase NAD+ levels.

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8. Natural Stacks NMN Capsules

Natural Stacks is a supplement brand that I have trusted for years as they have led the way for me in being transparent in their sourcing and testing of their supplement ingredients. It is great to see Natural Stacks now make a NMN supplement in capsule form combined with Vit B3 and TMG. For some people, they might just want pure NMN powder, but the Natural Stacks NMN product is a great choice if you want to try an NMN supplement to see how it makes you feel. I wasn’t able to find their certificate of analysis yet for their NMN product.

How to Choose a NAD+ Supplement

These are the things to consider before buying a NAD supplement:

1. Does the brand provide a certificate of analysis to prove purity and validation that it contains the amount of active ingredient as advertised per serving dose
2. What is the dose per serving to make sure you get the amount of active ingredient that you want
3. What type of form does the NAD booster come in e.g. powder, tablet, capsule, sublingual liquid etc…
4. Are there any other active ingredients in the product that you also want or not want to have
5. What is the cost per serving to see which product is the best deal or most cost effective for you
6. What is the shipping policy of the brand to make sure you can get it delivered to you
7. Do people mention the brand as a recommended choice on popular online forums

What is NAD+?

NAD+ stands for nicotinamide adenine dinucleotide and is a coenzyme for redox reactions, which means NAD+ is involved in energy metabolism and production in our mitochondria.

(Source: 1, 2)

What Is the Difference Between NAD, NAD+ and NADH?

NAD, NAD+ and NADH are three acronyms that used interchangeably when talking nicotinamide adenine dinucleotide supplements, but they are chemically different.

NAD+ is the oxidised version of NAD.

NADH stands for nicotinamide adenine dinucleotide + hydrogen, but is a minority species to NAD(+) under most physiologic conditions. NADH is bound to a hydride and NAD+ is not.

(Source: 1, 2, 3)

What Is the Difference Between NAD, NMN and NR?

NMN and NR are dietary forms of vitamin B3 and are precursors to NAD+.

NMN and NR are thought to be NAD boosters, but their appears to be lots of debate as to which one is better for elevating NAD levels.

(Source)

Recommended Dosages

The suggested dose for NAD+ supplements will depend on which NAD precursor (tryptophan, nicotinamide, nicotinic acid, nicotinamide riboside, nicotinamide mononucleotide) you are taking.

What Are the Benefits of NAD+?

The potential beneficial functions of nicotinamide adenine dinucleotide precursors are being studied in these areas of research:

• Aging
• Diabetes
• Alzheimer’s disease

(Source: 1)

What Are the Natural Food Sources of Nicotinamide Adenine Dinucleotide?

NAD+ is not found in naturally food, but its precursors like NMN are.

Nicotinamide adenine dinucleotide precursors are found in:

• Edamame
• Broccoli
• Cabbage
• Cucumber
• Avocados
• Mushrooms
• Tomatoes
• Raw-beef
• Shrimp

(Source)

Is Nicotinamide Adenine Dinucleotide Safe?

According to recent research studies we reviewed, NMN supplementation is safe and well tolerated in humans with dosages from 500 mg per day up to 2000 mg per day.

Possible Side-Effects

Here is a list of possible side effects when taking NAD supplements:

• Itchiness
• Dizziness
• Sweating
• Nausea
• Skin rash
• Flushing
• Leg cramps
• Increased bruising

(Source: 1, 2)

NAD+ Supplements Frequently Asked Questions

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