What Are the Best NAD+ Supplements?

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Supplements on a plate
What Are the Best NAD Supplements?
Reviewed by the BioHackers Lab Team | Last updated: January 16, 2023

The best nicotinamide adenine dinucleotide (NAD) supplement brands are:

Taking a good NAD+ supplement is thought to help boost your NAD levels, which could support energy production in our mitochondria, help repair DNA and support other systems in the body.

I was interested to find out what are some of the best nicotinamide adenine dinucleotide (NAD) supplements for me to review.

So, I went out researching online for what are some of the highest rated & most recommended NAD+ supplement products and brands available to buy online.

The Best NAD+ Supplements in 2023

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Here is a list of recommended NAD+ supplements on the market we reviewed for you to compare.


1. Renue By Science Lipo NAD+ Complete

Bottle of Renue by Science NAD+ Complete supplement bottle
Image: Renue By Science
Overview
  • Supplement Form: Capsules
  • NAD Dose: 95 mg
  • NR Dose: 80 mg
  • NMN Dose: 125 mg
  • Total Amount: 90 capsules
  • Chemical Certificate Analysis found on the product page
  • Used in NAD+ clinics
  • Website has useful list of research links and articles
  • Anti-aging supplementation is their product focus
  • Have a contact telephone number and email
Use the Renue By Science coupon code – Biohackers10 – at the RENUE BY SCIENCE website here to get a nice discount on their NMN supplements.

Renue By Science (previously known as Alive By Nature and Alive By Science) makes a unique 3-in-1 NAD supplement product, which contains NAD, NMN and NR wrapped in liposomes that are said to protect the active ingredients and help get them into the bloodstream. The say they created the first ever sublingual NMN supplement. They market themselves as triple lab tested for quality assurance and do provide the COA certificates on their product pages we reviewed.


2. Do Not Age NMN Capsules

Bottle of Do Not Age NMN supplement
Image: Do Not Age
Overview
  • Supplement Form: Capsules
  • NMN Dose: 500 mg
  • Capsule Count: 60 or 366 capsules
  • Chemical Certificate Analysis found on the product page
  • Anti-aging supplementation is the brands product focus
  • Have a customer contact email and address
  • Ship to the US, Canada, UK, Australia and Many Other Countries
Use the Do Not Age coupon code – BIOHACKERSLAB – at the DO NOT AGE website here to get a nice discount on their NMN supplements.

Do Not Age is a NMN brand that sells a lot of longevity specific supplements including pure NMN. They sell NMN capsules only, so no powder option. Their suggested serving is to take 2 capsules to get a 1000mg dose. Do Not Age guarantee the purity of the product on delivery to you as they say that they refrigerate the NMN right until the courier collects it from them. They do provide their latest certificate of analysis proof on their product page when we reviewed it.


3. Tru Niagen Nicotinamide Riboside

Tru Niagen supplement bottles of 30 and 90 capsules
Image: Tru Niagen
Overview
  • Capsule Type: Vegetarian
  • NR Dose: 300 mg
  • Capsule Count: 60 capsules per bottle
  • Vegetarian capsules are lightweight and easy to swallow
  • Available in different quantity options from single bottle to packs of 2 or 3 bottles and in subscription orders
  • Only has to be taken once per day
  • Website is full of useful resources, and the about section details every member of their scientific advisory and leadership boards
  • Nicotinamide riboside is their only product, which means all of their focus is dedicated to it
Buy it from the Tru Niagen website

Click to buy product on Amazon

Tru Niagen uses NIAGEN, the patented NR product owned by ChromaDex,. Dr. Charles Brenner PhD. who discovered nicotinamide riboside can help raise NAD levels in 2004, is on the scientific advisory board. The Tru Niagen website offers a lot of educational insight on the science behind why nicotinamide riboside is important for cellular function. (ref)


4. Wonderfeel Youngr NMN Capsules

Bottle of Wonderfeel NMN supplement 60 capsules
Image: Wonderfeel
Overview
  • Supplement Form: 100% Vegan Capsules
  • NMN Dose: 900 mg
  • Capsule Count: 60 capsules
  • Will provide a certificate of analysis via customer support
  • Will ship to the US, Canada and UK
  • Provide well written and referenced articles on their website

Click for current price button

The Wonderfeel brand are a US brand from San Francisco who have been in operation since 2018. The Wonderfeel Youngr NMN supplement was developed by Andrew Salzman, MD. You are able to ask for their recent certificate of analysis by emailing support; it is not published on the website. The 900 mg dosage of NMN is said to be based on research papers finding that amount appears to be the best.


5. Thorne NiaCel 400 Nicotinamide Riboside

Thorne NiaCel 400 Nicotinamide Riboside

Overview
  • Capsule Type: Vegetarian
  • NR Dose: 415 mg
  • TMC Dose: 85 mg
  • Capsule count: 60 capsules per bottle
  • Free of gluten, metallic colorants, soy, eggs, dairy, stearates, BPA, artificial preservatives, high fructose corn syrup, nuts and banned substances
  • The company markets that they do four rounds of testing their supplements
  • They are cGMP certified in the US and TGA certified in Australia

Click to buy product on Amazon

The Thorne NiaCel 400 formulation is a good option for someone wanting a NR supplement that combines both NR and betaine anhydrous to possibly help enhance their NAD levels. This product contains 85 mg of betaine anhydrous. (ref)


6. Elysium Health Basis NR Supplement

Tub of Elysium Health NAD+ Supplement
Image: Elysium Health
Overview
  • Supplement Form: Capsules
  • NR-E Dose: 250 mg
  • Capsule Count: 60 capsules
  • Shown to Increase NAD+ Levels in an RCT Study
  • Easy to find certificate of analysis on their website
  • Easy to find customer support email and telephone number
  • Capsule option only
  • Can ship to the US and Canada
Click for current price of product

Elysium Health Basis supplement is contains a patent pending form of NR called crystalline nicotinamide riboside (NR-E). The product also contains 50mg of Pterostilbene which is said to work together with the NR to help boost NAD+ levels. The product is NSF Certified for Sport and they link to their ingredient quality lots testing results. Their products was also shown in an RCT study to increase NAD+ levels.


7. Natural Stacks NMN Capsules

Bottle of Natural Stacks NMN supplement
Image: Natural Stacks
Overview
  • Supplement Form: capsules
  • NMN Dose: 250 mg
  • Capsule Count: 60 capsules
  • Brand has a good track history of being transparent about ingredient quality and testing
  • Brain health is their product focus
  • Have a customer contact telephone number and email
Use the Natural Stacks promo code – biohackerslab – at the Natural Stacks website here to get a nice discount on your order.

Natural Stacks is a supplement brand that I have trusted for years as they have led the way for me in being transparent in their sourcing and testing of their supplement ingredients. It is great to see Natural Stacks now make a NMN supplement in capsule form combined with Vit B3 and TMG. For some people, they might just want pure NMN powder, but the Natural Stacks NMN product is a great choice if you want to try an NMN supplement to see how it makes you feel. I wasn’t able to find their certificate of analysis yet for their NMN product.


8. Quicksilver NAD+ Gold Liposomal NMN

Bottle of Quicksilver Scientific NMN supplement
Overview
  • Supplement Form: Liposomal liquid
  • NMN Dose: 50 mg per remommnded serving of 2 pumps
  • Serving Count: 50 servings per bottle
  • Company has been around a long time
  • Products are said to tested for COA, Potency, Microbial, Heavy Metals, Pesticide Residue, Particle Sizing Tests, and Ingredient Identity Tests
  • Anti-aging and detox supplementation are their product focus
  • Have customer service enquiries available at their physical store, customer support contact telephone number and email
Use the Quicksilver Scientific promo code – BIOHACKERSLAB – at the Quicksilver Scientific website here to get a nice discount on your order.
Buy it from the Quicksilver Scientific website

The Quicksilver NMN supplement is called, Quicksilver NAD+ Gold. This product is the only one reviewed that delivers NMN in a liposomal form. When I was watching the video on their site with Dr Christopher Shade, PhD it appears that liposomal NMN might be more bioavailable than NMN in a powder form. It also contains 50 mg of TMG (betaine) to help assist with methylation.


9. Double Wood Supplements NMN Capsules

Bottle of Double Wood nmn 60 capsules
Image: Double Wood
Overview
  • Supplement Form: Bovine Gelatin Capsule
  • NMN Dose: 125 mg per capsule
  • Capsule Count: 60 capsules
  • Good amount of information on their website
  • Gluten-free, soy-free, non-GMO certified
  • Easy to find customer support email and telephone number
Buy it from the Double Wood website

Click for current price button

Double Wood makes a nicotinamide mononucleotide capsule that you swallow. This might not be the best absorption solution. You can also buy the Double Wood Supplements NMN powder option. They do provide easy to find links to their COA results and third party testing on their website. It is suggested you take one tablet in the morning and one in the early afternoon as a minimum. You can take up to 8 capsules over a course of a day. Take before eating any food. This product is not suitable for vegans and the capsule option does also contain rice flour.


10. ProHealth Longevity NMN Pro 150 Tablets

ProHealth Longevity Nicotinamide Mononucleotide Supplement

Overview
  • Supplement Form: Tablets
  • NMN Dose: 1000 mg
  • Capsule Count: 60 capsules
  • Easy to find certificate of analysis on their website
  • Easy to find customer support email and telephone number
  • Have bulk powder bags, lozenges & tablet options
  • Company is 30+ years old

Click for current price button

The ProHealth Longevity NMN supplement is an interesting option as they state they have the highest quality NMN available. This is because they source the NMN they sell from the biotech company that supplied the product for the first human research trial on NMN safety. They also state they have a NMN product that is stable at room temperature. The one thing to note is that the tablets also contain organic rice flour. (ref)


Buyers Guide on NAD+ Supplements

What is NAD+?

NAD+ stands for nicotinamide adenine dinucleotide and is a coenzyme for redox reactions, which means NAD+ is involved in energy metabolism and production in our mitochondria.

(Source: 1, 2)

What Is the Difference Between NAD, NAD+ and NADH?

NAD, NAD+ and NADH are three acronyms that used interchangeably when talking nicotinamide adenine dinucleotide supplements, but they are chemically different.

NAD+ is the oxidised version of NAD.

NADH stands for nicotinamide adenine dinucleotide + hydrogen, but is a minority species to NAD(+) under most physiologic conditions. NADH is bound to a hydride and NAD+ is not.

(Source: 1, 2, 3)

What Is the Difference Between NAD, NMN and NR?

NMN and NR are dietary forms of vitamin B3 and are precursors to NAD+.

NMN and NR are thought to be NAD boosters, but their appears to be lots of debate as to which one is better for elevating NAD levels.

(Source)

Recommended Dosages

The suggested dose for NAD+ supplements will depend on which NAD precursor (tryptophan, nicotinamide, nicotinic acid, nicotinamide riboside, nicotinamide mononucleotide) you are taking.

What Are the Benefits of NAD+?

The potential beneficial functions of nicotinamide adenine dinucleotide precursors are being studied in these areas of research:

(Source: 1)

What Are the Natural Food Sources of Nicotinamide Adenine Dinucleotide?

NAD+ is not found in naturally food, but its precursors like NMN are.

Nicotinamide adenine dinucleotide precursors are found in:

(Source)

Is Nicotinamide Adenine Dinucleotide Safe?

According to recent research studies we reviewed, NMN supplementation is safe and well tolerated in humans with dosages from 500 mg per day up to 2000 mg per day.

Possible Side-Effects

Here is a list of possible side effects when taking NAD supplements:

(Source: 1, 2)

NAD+ Supplements Frequently Asked Questions

How Do You Know if NAD+ Is Working?

The best way to know if your NAD supplement is working is by testing your NAD levels to see if they have increased or not.

When is the Best Time of Day to Take NAD+?

According to research from the University of Waterloo the best time to take an NAD supplement is 6 hours after waking up in the morning, but this is age dependant.

Can You Take NAD on an Empty Stomach?

Yes, you can take an NAD+ supplement on an empty stomach.

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