The Best Nicotinamide Riboside Supplements in 2020 Reviewed

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What is the Best Nicotinamide Riboside to Buy?
Reviewed by the BioHackers Lab Team | Last updated: August 2, 2020

I was interested to find out what are some of the best nicotinamide riboside supplements for me to review.

Taking a good nicotinamide supplement is thought to help NAD+ energy production in our mitochondria.

So I went out researching online for what are some of the highest rated & most recommended nicotinamide supplement products and brands available to buy online.

The Best Nicotinamide Riboside Supplements in 2020

Here is a list of recommended NAD+ supplements for you to compare.



1. Tru Niagen Nicotinamide Riboside

Tru Niagen supplement bottles of 30 and 90 capsules
Overview
  • Capsule Type: Vegetarian
  • NR Dose: 300 mg
  • Capsule Count: 60 capsules per bottle

Tru Niagen uses NIAGEN, the patented NR product owned by ChromaDex,. Dr. Charles Brenner PhD. who discovered nicotinamide riboside can help raise NAD levels in 2004, is on the scientific advisory board. The Tru Niagen website offers a lot of educational insight on the science behind why nicotinamide riboside is important for cellular function. (ref)

  • Vegetarian capsules are lightweight and easy to swallow
  • Available in different quantity options from single bottle to packs of 2 or 3 bottles and in subscription orders
  • Only has to be taken once per day
  • Website is full of useful resources, and the about section details every member of their scientific advisory and leadership boards
  • Nicotinamide riboside is their only product, which means all of their focus is dedicated to it

Click to buy product on Amazon



2. Life Extension NAD+ Cell Regenerator Nicotinamide Riboside

Life Extension nad+ cell regenerator supplement bottle
Overview
  • Capsule Type: Vegetarian
  • NR Dose: 100 mg and 300 mg options
  • Capsule Count: 30 capsules per bottle
Click to buy product on Life Extension

Life Extension uses NIAGEN® nicotinamide riboside in its NAD+ Cell Regenerator supplement formulation. There are two options with one containing 100 mg and the other 300 mg of NR per capsule. Life Extension is a good option as they are a brand I trust to provide the best dosages and trust their ingredients are what they state on the label. The company has been around for over 35 years and make over 350 different vitamins and supplements. (ref)

  • Life Extension is a well-established company with hundreds of supplements available, as well as a lab testing service and magazine
  • According to self-implemented customer surveys, 98% of customers recommend their products to friends and family
  • Their website is extensive, featuring health education pages, a news section, and a supplement guide

Click to buy product on Amazon



3. Life Extension Optimized NAD+ Cell Regenerator and Resveratrol

Overview
  • Capsule Type: Vegetarian
  • NR Dose: 300 mg
  • Resveratrol Dose: 100 mg
  • Capsule Count: 30 capsules per bottle
Click to buy product on Life Extension

The Life Extension Optimzed NAD+ Cell Regenerator and Resveratrol formulation also uses NIAGEN® nicotinamide riboside. It contains the bioflavonoid, quercetin, which can help improve the absorption of resveratrol. This Life Extension supplement is a good option for those who want the benefits of taking resveratrol and NR all in one capsule.



4. Thorne ResveraCel Nicotinamide Riboside

Thorne Research ResveraCel Nicotinamide Riboside

Overview
  • Capsule Type: Vegetarian
  • NR Dose: 300 mg
  • Resveratrol Dose: 150 mg
  • Capsule count: 60 capsules per bottle

Click to buy product on Amazon

The Thorne ResveraCel formulation is another good option for someone wanting one supplement that combines both NR and flavonoids to possibly help enhance sirtuin activity. This product contains 50 mg more resveratrol and 235 mg more quercetin per serving than the Life Extension option. Thorne also use NIAGEN® nicotinamide riboside in their ingredient list. (ref)

  • Free of gluten, metallic colorants, soy, eggs, dairy, stearates, BPA, artificial preservatives, high fructose corn syrup, nuts and banned substances
  • The company markets that they do four rounds of testing their supplements
  • They are cGMP certified in the US and TGA certified in Australia


5. Cytoplan Nicotinamide Riboside

Bottle of Cytoplan nicotinamide riboside supplement
Overview
  • Capsule Type: Vegetarian
  • NR Dose: 100 mg
  • Capsule count: 60 capsules per bottle
Click for current price of product

Cytoplan is brand that is only available in the UK. Their NR supplement contains 100 mg of nicotinamide riboside. You may need to order this through an approved Cytoplan practitioner.

6. Genex Nicotinamide Riboside

Genex Nicotinamide Riboside

Overview
  • Capsule Type: Vegetarian
  • NR Dose: 300 mg
  • Capsule count: 60

Click to buy product on Amazon

Genex Formulas is supplement company focused on making anti-aging supplements. They used to sell an NR product, but it appears their NR product is no longer available at the time of review. They still sell nicotinamide mononucleotide and resveratrol, and some of their products are third-party certified. On their website they do have a helpful page that explains the science behind NAD+ and its role in the body, as well as how nicotinamide riboside impacts NAD+ levels. (ref)



7. HPN Nutraceuticals Nicotinamide Riboside Metabolic Repair

HPN Nutraceuticals Nicotinamide Riboside Metabolic Repair

Overview
  • Capsule Type: Vegetarian
  • NR Dose: 250 mg
  • Capsule count: 60

Click to buy product on Amazon

HPN Nutraceuticals sells a handful of different supplements, including resveratrol, omega-3 and glucoside. They used to sell an NR product, but it appears their NR product is no longer available at the time of review. (ref)



Frequently Asked Questions

I know you were looking for what are the best options, but here is some more detail as to why we might need nicotinamide riboside products to help us make more NAD+.

What is Nicotinamide Riboside?

Nicotinamide riboside (NR) is a form for vitamin B3 that has been shown to increase levels of nicotinamide adenine dinucleotide (a.k.a NAD+).

Nicotinamide riboside is not the same as the other forms of vitamin B3, nicotinic acid (niacin) & nicotinamide.

Here are each of the forms in which vitamin B3 is found:

Recommended Dosages

The suggested dose for nicotinamide riboside is anywhere from 1 to 200 mg per day. Higher doses have shown minimal adverse effects, but any side effects may be more prominent at higher doses. Users may notice greater differences in energy with higher doses. (ref)

What Are the Benefits of Using Nicotinamide Riboside?

The potential beneficial functions of nicotinamide riboside are as follows:

The benefits of supplementing with nicotinamide riboside appear to be numerous. Although some tests have been done, more knowledge is needed to confirm its uses. (ref)

Preclinical trials have shown NAD+ to have anti-aging properties and it helps to generate energy in tissues such as muscle, liver and brain.

Supplementing with a capsule makes it easier to get a more effective dose.

How Does Nicotinamide Riboside Work?

Nicotinamide riboside is one of NAD+ precursors and helps to bypass the enzyme called NAMPT which is a rate limiting enzyme for creating NAD+. (ref)(ref)

NAD+ is in every living cell in the human body and plays a role in metabolism, DNA repair and cell signalling.

What Is the Science Behind Nicotinamide Riboside?

The reason nicotinamide riboside is so beneficial is that it is converted into NAD+ in the body. NAD+ is important for energy, mitochondria and the sleep cycle. (ref)

It also activates the following:

What Are the Natural Food Sources of Nicotinamide Riboside?

Nicotinamide riboside is found in:

Is Nicotinamide Riboside Safe?

Nicotinamide riboside is a naturally occurring form of vitamin B3 and is considered very safe. Even at exceptionally high doses, there is no risk of death. The only precaution is for athletes, as higher doses may negatively affect exercise performance.

Basically, all dosages are considered safe, although most nicotinamide riboside supplements have not been approved by the FDA and should be taken with caution and only after consulting with a physician.

Possible Side Effects

There is no human evidence to show any side effects from taking nicotinamide riboside; however, in animal tests, there may be a decrease in physical performance.

If this applies to humans as well, which we don’t currently know, it is only relevant for athletes or people concerned with athletic performance. Even at high doses up to 5000 mg, there is no risk of overdose or death and only minimal adverse effects have been seen once the dose is increased to 300 mg or higher. (ref)

Related Products

Last updated: August 2, 2020

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