The best nicotinamide mononucleotide (NMN) supplement brands are:
Why do people take NMN supplements? It is mainly to try help boost the NAD+ energy production in their mitochondria & activate SIRT1. The reasons why are to support healthy aging, plus, to try get some of the promising health benefits mentioned in studies researching NMN dietary supplementation.
I was interested to find out what are some of the best NMN supplements on the market for me to review.
So, I went out researching online for what are some of the highest rated & most recommended NMN supplement products and brands available to buy online.
What Is the Best NMN on the Market?
The Renue By Science NMN supplement range has been our readers favorite for years now.
The best NMN brand we would recommend is Renue By Science. They have been producing a great variety of NMN products for several years now to suit all needs, they provide a certificate of analysis for purity confirmation and have been a readers favorite for many years now.
The Best NMN Supplements in 2023
Here is a list of recommended NMN supplements on the market we reviewed for you to compare.
1. Renue By Science Pure NMN Powder
- Supplement Form: Powder
- NMN Dose: 500 mg
- Total Amount: 100 grams
- Chemical Certificate Analysis found on the product page
- Used in NAD+ clinics
- Website has useful list of research links and articles
- Anti-aging supplementation is their product focus
- Have a contact telephone number and email
Renue By Science (formerly known as Alive By Nature & Alive By Science) is one of the most transparent NMN brands I could find promoting the benefits of NMN supplementation. They provide either under the tongue (sublingual) tablets or NMN powders. The say they created the first ever sublingual NMN supplement. Contains monk fruit extract to help with the taste. They market themselves as triple lab tested for quality assurance and do provide the third party testing COA certificates on their NMN product pages we reviewed. (ref)
2. Do Not Age NMN Capsules
- Supplement Form: Capsules
- NMN Dose: 500 mg
- Capsule Count: 60 or 366 capsules
- Chemical Certificate Analysis found on the product page
- Anti-aging supplementation is the brands product focus
- Have a customer contact email and address
- Ship to the US, Canada, UK, Australia and Many Other Countries
Do Not Age is a NMN brand that sells a lot of longevity specific supplements including pure NMN. They sell NMN capsules only, so no powder option. Their suggested serving is to take 2 capsules to get a 1000mg dose. Do Not Age guarantee the purity of the product on delivery to you as they say that they refrigerate the NMN right until the courier collects it from them. They do provide their latest certificate of analysis proof on their product page when we reviewed it.
3. Wonderfeel Youngr NMN Capsules
- Supplement Form: 100% Vegan Capsules
- NMN Dose: 900 mg
- Capsule Count: 60 capsules
- 900 mg Dose per Serving is Backed by Research Studies
- Will provide a certificate of analysis via customer support
- Will ship to the US, Canada
- Provide well written and referenced articles on their website
- Subscribe and Save $15 Option
The Wonderfeel brand are a US brand from San Francisco who have been in operation since 2018. The Wonderfeel Youngr NMN supplement was developed by Andrew Salzman, MD. You are able to ask for their recent certificate of analysis by emailing support; it is not published on the website. The 900 mg dosage of NMN is said to be based on research papers finding that amount appears to be the best.
4. ProHealth Longevity NMN Pro 150 Tablets
- Supplement Form: Tablets
- NMN Dose: 1000 mg
- Capsule Count: 60 capsules
- Easy to find certificate of analysis on their website
- Easy to find customer support email and telephone number
- Have bulk powder bags, lozenges & tablet options
- Company is 30+ years old
The ProHealth Longevity NMN supplement is an interesting option as they state they have the highest quality NMN available. This is because they source the NMN they sell from the biotech company that supplied the product for the first human research trial on NMN safety. They also state they have a NMN product that is stable at room temperature. The one thing to note is that the tablets also contain organic rice flour. (ref)
5. Verso Cell Being NMN Capsules
- Supplement Form: Capsules
- NMN Dose: 250 mg
- Capsule Count: 60 capsules
- Easy to find certificate of analysis on their website
- Easy to find customer support email
- Capsule option only
- NMN is made in the USA
- Stored in commercial refrigerators to maintain stability
Verso NMN supplement is called Verso cell being and contains 250 mg of NMN, plus Trans-Resveratrol and TMG (trimethylglycine). You can buy a single pack with 60 capsules or you can buy in bulk with 12 packs, which makes works out cheaper. The NMN product is shipped from commercial refrigerators in Southern California and the brand lets you know the address. Verso is the same NMN brand you would have seen Thomas DeLauer mentioning on his YouTube channel.
6. Natural Stacks NMN Capsules
- Supplement Form: capsules
- NMN Dose: 250 mg
- Capsule Count: 60 capsules
- Brand has a good track history of being transparent about ingredient quality and testing
- Brain health is their product focus
- Have a customer contact telephone number and email
Natural Stacks is a supplement brand that I have trusted for years as they have led the way for me in being transparent in their sourcing and testing of their supplement ingredients. It is great to see Natural Stacks now make a NMN supplement in capsule form combined with Vit B3 and TMG. For some people, they might just want pure NMN powder, but the Natural Stacks NMN product is a great choice if you want to try an NMN supplement to see how it makes you feel. I wasn’t able to find their certificate of analysis yet for their NMN product.
7. Quicksilver NAD+ Gold Liposomal NMN
- Supplement Form: Liposomal liquid
- NMN Dose: 50 mg per remommnded serving of 2 pumps
- Serving Count: 50 servings per bottle
- Company has been around a long time
- Products are said to tested for COA, Potency, Microbial, Heavy Metals, Pesticide Residue, Particle Sizing Tests, and Ingredient Identity Tests
- Anti-aging and detox supplementation are their product focus
- Have customer service enquiries available at their physical store, customer support contact telephone number and email
The Quicksilver NMN supplement is called, Quicksilver NAD+ Gold. This product is the only one reviewed that delivers NMN in a liposomal form. When I was watching the video on their site with Dr Christopher Shade, PhD it appears that liposomal NMN might be more bioavailable than NMN in a powder form. It also contains 50 mg of TMG (betaine) to help assist with methylation.
8. Double Wood Supplements NMN Capsules
- Supplement Form: Bovine Gelatin Capsule
- NMN Dose: 125 mg per capsule
- Capsule Count: 60 capsules
- Bulk powder option available
- Good amount of information on their website
- Gluten-free, soy-free, non-GMO certified
- Easy to find customer support email and telephone number
Double Wood makes a nicotinamide mononucleotide capsule that you swallow. This might not be the best absorption solution. You can also buy the Double Wood Supplements NMN powder option. They do provide easy to find links to their COA results and third party testing on their website. It is suggested you take one tablet in the morning and one in the early afternoon as a minimum. You can take up to 8 capsules over a course of a day. Take before eating any food. This product is not suitable for vegans and the capsule option does also contain rice flour.
9. MAAC10 Nicotinamide Mononucleotide Capsules
- Supplement Form: Vegetarian Capsules
- NMN Dose: 125 mg
- Capsule Count: 30 capsules
- Good amount of information and research links on their website
- Gluten-free, soy-free, non-GMO certified
- Easy to find customer support email and telephone number
MAAC10 NMN supplement looks to be another brand good to consider. They also display their certificate of analysis, which shows the recent test. The result shows they do provide slightly more NMN (138 mg) per capsule vs what they advertise on the label (125 mg) per capsule. MAAC10 give a quality and purity guarantee. They also reference this tweet from Dr David Sinclair why NMN capsules are fine to take vs sublingual tablets. (ref)
10. GeneX Formulas NMN Capsules
- Supplement Form: Vegetarian Capsules
- NMN Dose: 125 mg
- Capsule Count: 60 capsules
- Capsules and powder option
- CoA available on their website
- Customer support email and phone number available
GeneX Formulas is another brand that only focuses on making anti-aging supplements. The make NMN sublingual powder and capsules options. The also follow the other brands who supply around 125 mg per capsule. They also show they have recent 3rd party lab testing certificates they display to verify their NMN dosage. They have a nice timeline reference of the science from 1983. (ref)
How to Choose a NMN Supplement
These are the things to consider before buying an NMN supplement:
- Does the brand provide a certificate of analysis to prove purity and validation that it contains the amount of active ingredient as advertised per serving dose
- What is the dose per serving to make sure you get the amount of NMN that you want
- What type of form does the NMN come in e.g. powder, tablet, capsule, sublingual liquid etc…
- Are there any other active ingredients in the product that you want or not
- What is the cost per serving to see which product is the best deal or most cost effective for you
- What is the shipping policy of the brand to make sure you can get it delivered to you
- Do people mention the brand as a recommended choice on popular online forums
Why Take an NMN Supplement?
The main reason why people take and NMN supplement is because NMN is a form of vitamin B3 and is a NAD precursor.
NAD precursors are being studied for evidence on how much they might influence anti aging properties like the hallmarks of aging.
The bioavailability of taking a NMN supplement is thought to be better than taking an NAD supplement to help raise the NAD levels in our bloodstream.
People will normally first test their NAD+ levels then supplement with NMN, or NR, to try help raise their NAD+ levels to an optimal range.
What Are the Types of NMN Available?
There are two forms of NMN available which are: α-NMN (alpha-nicotinamide mononucleotide) and β-NMN (beta-nicotinamide mononucleotide). The active form of NMN is known as β-NMN or nicotinamide mononucleotide.
(Source)
What Are the Benefits of Using Nicotinamide Mononucleotide?
The potential beneficial functions of NMN are as follows:
- Improves NAD+ levels
- Reverse aging of blood vessels
- Aid growth of muscle
- Lower body fat
- Help improve insulin sensitivity
- Help repair DNA in our cells
- Increases energy levels
- Boost energy levels and stamina during exercise
- Used to prevent cognitive decline and help memory
(Source)
However, what we saw was that most of these are animal studies with a few on humans.
What Are the Recommended NMN Dosages?
The suggested dose for nicotinamide mononucleotide is anywhere from 250 mg to 1500 mg per day.
Dr David Sinclair PhD, a famous researcher in the biology of aging and genetics, publicly stated he takes 1g of NMN per day on a Joe Rogan podcast interview, which is the highest dose we came across someone taking per day.
What Are the Natural Food Sources of Nicotinamide Mononucleotide?
Nicotinamide mononucleotide is naturally found in the following foods:
- Edamame
- Broccoli
- Cabbage
- Cucumber
- Avocados
- Mushrooms
- Tomatoes
- Raw-beef
- Shrimp
(Source)
Is Nicotinamide Mononucleotide Safe?
According to recent research studies we reviewed, NMN supplementation is safe and well tolerated in humans with dosages from 500 mg per day up to 2000 mg per day.
What Are Possible Side-Effects from Taking NMN?
Here is a list of possible side effects when taking a NMN supplement:
- Itchiness
- Dizziness
- Sweating
- Nausea
- Skin rash
- Flushing
- Leg cramps
- Increased bruising
NMN Supplements Frequently Asked Questions
How Do You Know if NMN Is Working?
The best way to know if your NMN supplement is working is by testing your NAD levels to see if they have increased or not.
When is the Best Time of Day to Take NMN?
According to research from the University of Waterloo the best time to take an NMN supplement is 6 hours after waking up in the morning, but this is age dependant.
Can You Take NMN on an Empty Stomach?
Yes, you can take an NMN supplement on an empty stomach.
Where to Buy NMN Supplements?
You can currently buy NMN supplements directly from different suppliers via their online stores, but will only be able to buy on Amazon up until March 13 2023.
Sources
- Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns, Nadeeshani etl. 2022
- Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study, Liao et al. 2021
- Supplementation with NAD+ and Its Precursors to Prevent Cognitive Decline across Disease Contexts, Campbell J. 2021
- The Science Behind NMN–A Stable, Reliable NAD+Activator and Anti-Aging Molecule, Shade C. 2020
- Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice, Mills et al. 2016
- The first human clinical study for NMN has started in Japan, Tsubota K. 2016
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