The Best Glutathione Supplement Brands for 2023
The best glutathione supplement brands are:
- Renue By Science Liposomal Glutathione Supplement
- ProHealth S-Acetyl Glutathione Supplement
- Bulletproof Force Glutathione Supplement
- Alms Bio Liposomal Glutathione Supplement
- Healthy Origins Liposomal Glutathione Supplement
- Core Med Science Liposomal Glutathione Supplement
- Nutrivein Liposomal Glutathione Supplement
- Pure Encapsulation Liposomal Glutathione Supplement
- Double Wood Supplements S-Acetyl L-Glutathione Supplement
- Quicksilver Scientific Liposomal Glutathione Supplement
Glutathione (GSH) is a master antioxidant, which is why so many people are told to take a glutathione supplement to help assist their liver with a detox protocol, support their immune system or improve energy levels.
I was interested to find out what are some of the best glutathione supplements for me to review.
So, I went out researching online for what are some of the top rated & most recommended brands who make glutathione products that are available to buy online.
What is The Best Glutathione Brand on the Market?
Renue By Science are becoming an established leader in healthspan supplements, including their liposomal glutathione supplement.
The best glutathione brand we would recommend is Renue By Science. They are a US based brand who also can ship internationally. Their LIPO Glutathione is meant to compliment their other products which are all used to help support NAD levels for healthy aging. Their product range has been our readers favorite for several years now.
The Best Glutathione Supplements in 2025
Here is a list of recommended glutathione supplements on the market we reviewed for you to compare.
1. Renue By Science LIPO Glutathione
- 130 mg of L-Glutathione per serving
- Liposomal Glutathione
- Contains 90 servings per box
- Comes in Capsules
- Recommended dosage is 1 capsules every day
- One bottle will last 90 days if taking recommended serving once a day
Renue By Science is a leading healthspan supplement brand that sells a powdered liposomal form of glutathione. This is meant to help with bioavailability so that you can get the best absorption and avoid the digestion process breaking down most of it. You can also find their third party testing lab results to show purity and concentration is what is advertised on the nutrition label.
2. ProHealth S-Acetyl Glutathione Capsules
- 300 mg of Emothion® Glutathione per serving
- S-Acetyl Glutathione Form
- Contains 60 servings per Bottle
- Comes in Vegetarian Capsules
- Recommended dosage is 1 capsules every day
- One bottle will last 60 days if taking recommended serving once a day
ProHealth sells two forms of glutathione: s-acetyl GSH and reduced liposomal GSH. This s-acetyl glutathione product from ProHealth uses Emothion®, which according to the graph shown on Gnosis website was shown to raise blood levels by 69% compared to other commercial GSH sources. You will see there are other sources of glutathione used in other top rates glutathione products listed, but ProHealth is the only one that uses Emothion.
3. Bulletproof Force Glutathione Capsules
- 500 mg of CELLg8® Glutathione per serving
- Contains 30 servings per bottle
- Soft Gel Capsules
- Recommended dosage is take 3 capsules once per day
- One bottle will last 30 days if taking serving once per day

The Bulletproof Force capsules contain 500 mg of liposomal glutathione sourced from CELLg8® which they show according to this study that CELLg8 liposomal glutathione raises glutathione blood levels significantly more than the powder form of GSH. Bulletproof are the only brand I reviewed that sources CELLg8 liposomal glutathione. The fats used are phosphatidylcholine, palmitic and oleic acids. This proprietary blend is meant to help get you better absorption of glutathione at the small intestine. If you are a fan of the Bulletproof brand then this is the best choice for you.
4. Alms Bio Glutathione Mito-Therapy+ Gel Syringes

- 250 mg Glutathione per serving of 5ml
- Contains 20 servings per box
- Liquid Oral Syringe Dispenser
- Recommended dosage is take 5ml dose once ever other day
- One packet of 5 syringes that contain 4 servings in each and will last 40 days if taking serving once every other day
If anyone is looking for the original glutathione syringes that were available from the old Upgraded Self shop then this is the option for you. The Alms Bio gel syringes not only contain liposomal glutathione, but also PQQ and CoQ10 to assist your mitochondria. You should feel an energy boost soon after taking this. Their maintenance recommended dose is one serving every other day. You will need to refrigerate these syringes.
5. Healthy Origins L-Glutathione Capsules

- 500 mg Setria® L-Glutathione per serving
- Contains 150 servings per bottle
- Soft Gel Capsules
- Recommended dosage is take 1 capsule once per day
- One bottle will last 150 days if taking serving once per day

What I like about Healthy Origins glutathione capsules is they just contain 500 mg of active ingredient and nothing else. You are getting a lot of capsules at a high dose. This means a bottle will last you the longest out of all brands reviewed. This is a good option if you want to test for any benefit personally for you, and also if taking a dose daily for a long period of time.
6. Core Med Science Liposomal Glutathione Liquid

- 500 mg Setria® L-Glutathione per serving
- Contains 30 servings per bottle
- Liquid Bottle
- Recommended dosage is take 4ml of liquid once per day
- One bottle will last 30 days if taking serving once per day

For someone wanting a pourable liquid form glutathione the Core Med Science glutathione is a good choice. It is has a citrus flavor with added stevia to help mask the natural unpleasant taste of glutathione. It also contains a liposome proprietary blend, which I think is the same as all the others who use Setria® L-Glutathione. This product will also need refrigeration for storage.
5. Nutrivein Liposomal Glutathione Capsules

- 600 mg Setria® L-Glutathione per serving
- Contains 30 servings per bottle
- Soft Gel Capsules
- Recommended dosage is take 2 capsule once per day
- One bottle will last 30 days if taking serving once per day

The Nutrivein glutathione is one of the top rated brands available on Amazon that we reviewed. Their product is bottled in the USA with the active ingredient being Setria® L-Glutathione from Japan. You get a decent amount of serving per bottle. I like that they also have a simple ingredient list. They guarantee they are Vegan-friendly supplements.
7. Pure Encapsulation Liposomal Glutathione Capsules

- 250 mg Setria® Glutathione per serving
- Contains 60 servings per bottle
- Soft Gel Capsules
- Recommended dosage is take 1 capsule once to twice per day
- One bottle will last 30 days if taking serving twice per day

If you want a brand that has been around for a long time Pure Encapsulation glutathione is a good option for you. They also use the popular glutathione supplier Sertia® mixed in the BioGlute™ liposomal proprietary blend. The 250 mg dose should be enough for most people as a long-term solution.
8. Lipo Naturals Liposomal Glutathione Antioxidant Complex

- 500 mg Setria® L-Glutathione per serving
- Contains 30 servings per bottle
- Liquid resealable sachet
- Recommended dosage is take 15ml of liquid once per day
- One sachet will last 30 days if taking serving once per day

The Lipo Naturals brand is one that only makes two products: Liposomal Glutathione and Liposomal vitamin C. Like other brands they use Setria® L-Glutathione. What I like is they also list what are the natural flavors added for taste. These are fermented plum, mint and linseed. This liquid will need to be refrigerated and comes in a BPA resealable sachet. Just remember to shake each time before use.
9. Double Wood Supplements S-Acetyl L-Glutathione Capsules
- 100 mg Glutathione per serving
- Contains 60 servings per bottle
- Soft Gel Capsules
- Recommended dosage is take 1 capsules once per day
- One bottle will last 60 days if taking serving once per day
The Double Wood Supplements S-Acetyl L-Glutathione capsules are a good choice for those looking for the acetylated form of glutathione. There are good reasons to consider taking the acetylated form vs liposomal glutathione form like it not needing to be broken down by enzymes. You will easily find the current certificate of analysis and third party testing results on the Double Wood Supplements product page.
10. Quicksilver Scientific Liposomal Glutathione Liquid Spray
- 100 mg Opitac™ reduced liposomal glutathione per serving of 1ml
- Contains 50 servings per bottle
- Liquid pump dispenser
- Recommended dosage is to take 1ml as 2 pumps of liquid by mouth twice per day
- One bottle will last 25 days if taking serving twice per day

This is the only glutathione product that uses the Opitac™ L-Glutathione reduced raw ingredient from Japan. The taste is mint flavored with natural mint and citrus oils. It comes in a liquid spray pump form that needs refrigeration. They say they use a trademarked Quicksilver Delivery Systems® to improve bioavailability of their glutathione via the mouth. The supplement is made in the USA in their facility in Colorado. Quicksilver Scientific is a brand founded by Dr Christopher Shade, PhD that makes different detox supplements. This is a popular brand you will find at biohacking conferences.
Top 10 Glutathione Supplements Compared
Brand | Description |
---|---|
Renue by Science | Leader in healthy aging supplements that sells a liposomal form of glutathione |
ProHealth | Trusted company in the healthy aging supplement industry sells a unique S-AcetylGlutathione Supplement |
Bulletproof | Uses CELLg8 liposomal glutathione which has been shown to raise glutathione blood levels |
Alms Bio | Best brand for a unique liquid form of glutathione you take by drinking from a syrine |
Healthy Origins | Offers glutathione capsules that contain 500 mg of active ingredient and nothing else |
Core Med Science | Offers a pourable liquid form glutathione with a citrus flavor |
Nutrivein | One of the top rated brands available on Amazon. Their product is bottled in the USA with the active ingredient being Setria® L-Glutathione from Japan. |
Pure Encapsulation | A brand that has been around for a long time. They use the popular glutathione supplier Sertia® mixed in the BioGlute™ liposomal proprietary blend. |
Double Wood | Offers S-Acetyl L-Glutathione capsules for those looking for the acetylated form of glutathione |
Quicksilver Scientific | The only glutathione product that uses the Opitac™ L-Glutathione reduced raw ingredient from Japan. Comes in a liquid spray pump form |
Frequently Asked Questions
How Quickly Does Liposomal Glutathione Work?
Research has found that after 1 week of daily liposomal glutathione supplement intake that blood levels of glutathione had increased.
When Is the Best Time to Take Glutathione?
The best time to take a glutathione supplement might be in the evening, but we cannot find a definitive answer on this one.
Do You Take Glutathione With or Without Food?
You take liposomal glutathione without food and on an empty stomach.
How to Choose a Glutathione Supplement
These are the things to consider before buying an glutathione supplement:
- Does the brand provide a certificate of analysis to prove purity and validation that it contains the amount of active ingredient as advertised per serving dose
- What is the dose per serving to make sure you get the amount of glutathione that you want
- What type of form does the glutathione come in e.g. liposomal, powder, tablet, capsule, sublingual liquid etc…
- Are there any other active ingredients in the product that you want or not
- What is the cost per serving to see which product is the best deal or most cost effective for you
- What is the shipping policy of the brand to make sure you can get it delivered to you
- Do people mention the brand as a recommended choice on popular online forums
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